Chemical Constituents of Plants from the Genus Eupatorium (1904-2014).

Pei-Yu Liu, Dan Liu, Wei-Huan Li, Ting Zhao, Françoise Sauriol, Yu-Cheng Gu, Qing-Wen Shi, Man-Li Zhang

Journal: Chemistry & biodiversity 2016;12(10):1481-515

PMID: 26460556

Abstract

Eupatorium (family: Compositae), which comprises nearly 1200 species, is distributed throughout tropical America, Europe, Africa, and Asia. Up to now, the reported constituents from the genus Eupatorium involve flavonoids, terpenoids, pyrrolizidine alkaloids, phenylpropanoids, quinonoids, essential oils, and some others, altogether more than 300 compounds. Studies have shown that Eupatorium and its active principles possess a wide range of pharmacological activities, such as cytotoxic, antifungal, insecticidal, antibacterial, anti-inflammatory, and antinociceptive activities. Currently, effective monomeric compounds or active parts have been screened for pharmacological activities from Eupatorium in vivo and in vitro. Increasing amount of data supports application and exploitation for new drug development.

Address: Department of Natural Product Chemistry, School of Pharmaceutical Sciences, Hebei Medical University, 361 Zhongshan East Road, Shijiazhuang 050017 , P. R. China, (phone: +86-311-86265634).; Hebei United University Affiliated Hospital, Tangshan, P. R. China.; Department of Chemistry, Queen's University, Kingston, Ontario K7L 3N6, Canada.; Jealott's Hill International Research Centre, Syngenta, Berkshire RG42 6EY, UK.; Department of Natural Product Chemistry, School of Pharmaceutical Sciences, Hebei Medical University, 361 Zhongshan East Road, Shijiazhuang 050017 , P. R. China, (phone: +86-311-86265634). [email protected].; Department of Natural Product Chemistry, School of Pharmaceutical Sciences, Hebei Medical University, 361 Zhongshan East Road, Shijiazhuang 050017 , P. R. China, (phone: +86-311-86265634). [email protected].

DOI: 10.1002/cbdv.201400227

Link outs

Subscription / membership required

Full Text Sources:

https://doi.org/10.1002/cbdv.201400227

MeSH Terms: Analgesics, Anti-Infective Agents, Anti-Inflammatory Agents, Antineoplastic Agents, Phytogenic, Eupatorium, Humans, Organic Chemicals, Plant Extracts