Methods and considerations for the analysis and standardization of assessing muscle sympathetic nerve activity in humans.

Daniel W White, J Kevin Shoemaker, Peter B Raven

Journal: Autonomic neuroscience : basic & clinical 2016;193():12-21

PMID: 26299824

Abstract

The technique of microneurography and the assessment of muscle sympathetic nerve activity (MSNA) are used in laboratories throughout the world. The variables used to describe MSNA, and the criteria by which these variables are quantified from the integrated neurogram, vary among studies and laboratories and, therefore, can become confusing to those starting to learn the technique. Therefore, the purpose of this educational review is to discuss guidelines and standards for the assessment of sympathetic nervous activity through the collection and analysis of MSNA. This review will reiterate common practices in the collection of MSNA, but will also introduce considerations for the evaluation and physiological inference using MSNA.

Copyright © 2015 Elsevier B.V. All rights reserved.

Address: The Department of Kinesiology & Nutrition, University of Illinois at Chicago, Chicago, IL, USA. Electronic address: [email protected].; The School of Kinesiology, University of Western Ontario, London, ON, Canada.; Department of Integrative Physiology and Anatomy, University of North Texas Health Science Center, Fort Worth, TX, USA.
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