Iron Deficiency in Heart Failure: Looking Beyond Anaemia.

Christopher C Y Wong, Austin C C Ng, Leonard Kritharides, Andrew P Sindone

Journal: Heart, lung & circulation 2016;25(3):209-16

PMID: 26669811

Full Text on Elsevier Science View on PubMed

Abstract

Iron is an essential micronutrient in many cellular processes. Iron deficiency, with or without anaemia, is common in patients with chronic heart failure. Observational studies have shown iron deficiency to be associated with worse clinical outcomes and mortality. The treatment of iron deficiency in chronic heart failure patients using intravenous iron alone has shown promise in several clinical trials, although further studies which include larger populations and longer follow-up times are needed.

Copyright © 2015 Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ). Published by Elsevier B.V. All rights reserved.

Address: Cardiology Department, Concord Hospital, University of Sydney, Sydney, NSW, Australia.; Cardiology Department, Concord Hospital, University of Sydney, Sydney, NSW, Australia. Electronic address: [email protected].

DOI: 10.1016/j.hlc.2015.06.827

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MeSH Terms: Chronic Disease, Heart Failure, Humans, Iron, Iron Deficiencies