New World and Old World Leishmania Infections: A Practical Review.

Ines Kevric, Mark A Cappel, James H Keeling

Journal: Dermatologic clinics 2016;33(3):579-93

PMID: 26143433

Full Text on Elsevier Science View on PubMed

Abstract

Leishmaniasis is a parasitic infection endemic to more than 90 countries worldwide. As travel to endemic areas increases, dermatologists need to keep this entity in the differential for any chronic skin lesion in persons who may have had a possible exposure for any duration. It can be difficult to diagnose because manifestations are varied and sometimes subclinical. This article discusses the current state of epidemiology, pathogenesis, clinical presentation, diagnosis, and treatment options. A special focus is placed on cutaneous manifestations and their treatment.

Address: Department of Mayo Clinic, 4500 San Pablo Rd, Jacksonville, FL 32224, USA.; Department of Dermatology, Mayo Clinic, 4500 San Pablo Road South, Jacksonville, FL 32224, USA. Electronic address: [email protected].

DOI: 10.1016/j.det.2015.03.018

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MeSH Terms: Amphotericin B, Antimony Sodium Gluconate, Antiprotozoal Agents, Deoxycholic Acid, Drug Combinations, Humans, Incidence, Leishmania braziliensis, Leishmania donovani, Leishmania mexicana, Leishmania tropica, Leishmaniasis, Diffuse Cutaneous, Leishmaniasis, Mucocutaneous, Leishmaniasis, Visceral, Phosphorylcholine, Polymerase Chain Reaction, Travel