Monte Carlo design study for in vivo bone aluminum measurement using a low energy accelerator beam.

A Pejović-Milić, M L Arnold, F E McNeill, D R Chettle

Journal: Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 2000;53(4-5):657-64

PMID: 11003504

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Abstract

The need for aluminum monitoring exists in occupational medicine, as well as for the clinical monitoring of patients with renal dysfunction. After the development of an appropriate neutron source card, Monte Carlo simulations were made to design moderator/reflector assembly consisting of a polyethylene moderator (2 cm) and graphite reflector (30 cm), surrounded by a boronated (5%) wax (20 cm) and lead (1 cm) shield. This design should allow for the bone aluminum measurement of healthy subjects, but prior to that detailed microdosimetry is necessary to address a noticed disagreement between theoretical and experimental dose data.

Address: Department of Physics and Astronomy, McMaster University, Hamilton, ON, Canada. [email protected]

DOI: 10.1016/s0969-8043(00)00200-1

MeSH Terms: Aluminum, Bone and Bones, Computer Simulation, Facility Design and Construction, Fast Neutrons, Filtration, Hand, Humans, Models, Anatomic, Models, Biological, Monte Carlo Method, Neutron Activation Analysis, Particle Accelerators, Phantoms, Imaging, Protons, Radiation Protection