Is Acute Zonal Occult Outer Retinopathy an Autoimmune Condition? A Case Report and Literature Review.

Rami Abo-Shasha, Catherine C Smith, Chloe C Gottlieb, Stuart G Coupland

Journal: Ophthalmic surgery, lasers & imaging retina 2016;46(6):662-5

PMID: 26114848

Abstract

A 42-year-old woman with multiple sclerosis presented with focal decreased vision and photopsia in the left eye. Funduscopy and fluorescein angiography revealed focal chorioretinal atrophy, vascular attenuation, and bone spicules. Electroretinography revealed interocular reduction in b-wave amplitude, and Goldmann visual field perimetry studies revealed an inferior scotoma. The authors performed a literature review and conclude that the prevalence of acute zonal occult outer retinopathy in patients with autoimmune conditions may suggest that the condition is autoimmune in nature. Clinical history as well as funduscopic and retinal investigations are important in diagnosing acute zonal occult outer retinopathy.

DOI: 10.3928/23258160-20150610-11

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MeSH Terms: Adult, Autoimmune Diseases, Electroretinography, Female, Fluorescein Angiography, Humans, Multiple Sclerosis, Scotoma, Tomography, Optical Coherence, Visual Acuity, Visual Field Tests, Visual Fields, White Dot Syndromes