Primary angiomatoid melanoma as an exceptional morphologic pattern in cutaneous melanoma. A case report and review of the literature.

G Ramos-Rodríguez, C Ortiz-Hidalgo

Journal: Actas dermo-sifiliograficas 2016;106(3):e13-7

PMID: 25498159

Free Full Text on Ediciones Doyma, S.L. View on PubMed

Abstract

We report a case of angiomatoid melanoma on the right thigh of a 59-year-old man. The histologic growth pattern of the tumor mimicked vascular proliferation, and the cells lining the pseudovascular spaces were positive for protein S-100, HMB-45, and MITF-1. The differential diagnosis is with angiosarcoma and pseudovascular adenoid squamous cell carcinoma. The case we present is the fifth reported to date.

Address: Departamento de Anatomía Patológica, Hospital Regional Lic. Adolfo López Mateos ISSSTE, México DF, México.; Departamento de Patología Quirúrgica y Molecular, Centro Médico ABC, México DF, México; Departamento de Biología Celular y Tisular, Universidad Panamericana, México DF, México. Electronic address: [email protected].

DOI: 10.1016/j.ad.2014.09.002

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MeSH Terms: Adult, Aged, 80 and over, Carcinoma, Squamous Cell, Diagnosis, Differential, Hemangiosarcoma, Humans, Male, Melanoma, Melanoma-Specific Antigens, Microphthalmia-Associated Transcription Factor, Middle Aged, Mitotic Index, Neoplasm Proteins, S100 Proteins, Skin Neoplasms, gp100 Melanoma Antigen