Acrodermatitis enteropathica and other nutritional diseases of the folds (intertriginous areas).

Nikita Lakdawala, Jane M Grant-Kels

Journal: Clinics in dermatology 2016;33(4):414-9

PMID: 26051055

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Abstract

The appropriate intake and metabolism of vitamins and minerals are critical to maintaining homeostasis. Imbalance in essential nutrients, either through dietary excess or deficiency or disorders in metabolism, can result in a spectrum of dermatologic and systemic manifestations. Certain nutrient deficiencies produce a characteristic pattern of cutaneous eruption. Recognition of these patterns is important, as they can alert the physician to an underlying nutritional disease. We review nutritional diseases involving zinc, biotin, essential fatty acids, vitamin B6 (pyridoxine), and riboflavin that present specifically with intertriginous eruptions.

Address: Department of Dermatology, University of Connecticut Health Center, 21 South Road, Farmington, CT, 06030, USA.; Department of Dermatology, University of Connecticut Health Center, 21 South Road, Farmington, CT, 06030, USA. Electronic address: [email protected].

DOI: 10.1016/j.clindermatol.2015.04.002

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MeSH Terms: Acrodermatitis, Avitaminosis, Comorbidity, Deficiency Diseases, Fatty Acids, Essential, Female, Humans, Intertrigo, Male, Prevalence, Prognosis, Zinc