LQT1-phenotypes in hiPSC: Are we measuring the right thing?

Torsten Christ, András Horvath, Thomas Eschenhagen

Journal: Proceedings of the National Academy of Sciences of the United States of America 2015;112(16):E1968

PMID: 25795242

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Abstract

Address: Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany; and DZHK (German Centre for Cardiovascular Research), German Centre for Cardiovascular Research, partner site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany [email protected].; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany; and DZHK (German Centre for Cardiovascular Research), German Centre for Cardiovascular Research, partner site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany.

DOI: 10.1073/pnas.1503347112

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MeSH Terms: Humans, Induced Pluripotent Stem Cells, Jervell-Lange Nielsen Syndrome, KCNQ1 Potassium Channel, Models, Biological, Phenotype