Conversion from clinically isolated syndrome to multiple sclerosis: A large multicentre study.

Address: Blizard Institute, Queen Mary University of London, Barts and The London School of Medicine and Dentistry, UK/ Departments of Neurology and Biomedicine, University Hospital Basel, University of Basel, Switzerland.; Blizard Institute, Queen Mary University of London, Barts and The London School of Medicine and Dentistry, UK.; Wolfson Institute of Preventive Medicine, Queen Mary University of London, Barts and the London School for Medicine and Dentistry, UK.; Department of Neurology and INSPE, Vita-Salute San Raffaele University, Scientific Institute San Raffaele, Italy.; Department of Neurology, Erasmus MC University Medical Center, The Netherlands.; Centre of Multiple Sclerosis, City Clinical Hospital#31, Russia.; Institut de Génomique Fonctionelle, CNRS UMR5203, INSERM U661, Université Montpellier 1, Université Montpellier, France, and Hôpital Carémeau, France.; Department of Basic Medical Sciences, Neuroscience and Sense Organs, University of Bari, Italy.; Neuroimmunology Unit, Department of Clinical Neuroscience, Karolinska Institutet, Sweden.; Servei de Neurologia-Neuroimmunologia, Centre d'Esclerosi Múltiple de Catalunya (Cemcat), Institut de Receca Vall d'Hebron (VHIR), Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Spain.; Departments of Neurology and Clinical Chemistry, MS Center, Neurocampus Amsterdam, VU University Medical Centre Amsterdam, The Netherlands and BioMS-eu network.; Department of Neurology, Innsbruck Medical University, Austria.; Department of Radiology, Innsbruck Medical University, Austria.; Department of Health Sciences and IRCAD, Eastern Piedmont University, Italy.; Department of Neurology and Immunology, Hospital Ramón y Cajal, Spain.; Department of Neurology, Charles University in Prague, Czech Republic.; Department of Neurology, CSF Laboratory and MS Outpatient Unit, University of Ulm, Germany.; Center for Neuroimmunology and Department of Neurology. Institut d'investigacions Biomèdiques August Pi Sunyer (IDIBAPS) - Hospital Clinic of Barcelona, Spain.; Dr Orhan Öcalgiray Molecular Biology-Biotechnology and Genetics Research Centre, Istanbul Technical University, Turkey.; Department of Neurology, Istanbul University, Turkey.; Department of Neurology, Medical Faculty, Heinrich-Heine-University, Germany.; Department of Neurology, University of Szeged, Hungary.; C. Mondino National Neurological Institute, Italy.; Pôle de Neurosciences Cliniques, Service de Neurologie, Centre de Résonance Magnétique Biologique et Médicale, Centre Hospitalier Universitaire Timone, Laboratoire d'histocompatibilité, Etablissement Français du Sang Alpes Méditerrannée, Aix Marseille Université, France.; Department of Neurology, Medical University of Graz, Austria.; Department of Neurology, Université de Lyon, Université Claude Bernard-Lyon 1, France.; Clinic of Neurology, Belgrade University School of Medicine, Serbia.; Unit of Functional Imaging, Glostrup Hospital, University of Copenhagen, Denmark.; Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Sweden.; Neurology Unit, Dept. of Pathophysiology and Transplantation, University of Milan, Fondazione Cà Granda, IRCCS Policlinico.; KG Jebsen Centre for MS-Research, Department of Clinical Medicine, Haukeland University Hospital, University of Bergen, Norway.; Department of Neurology, University of Genoa, Italy.; Centre for Experimental Neurological Therapies, S. Andrea Hospital-site, Department of Neuroscience, Mental Health and Sensory Organs (NESMOS), Faculty of Medicine and Psychology, Sapienza University, Italy.; Department of Neurology of Hospital Británico of Buenos Aires, Argentina.; Department of Neurology, Medical University of Lublin, Poland.; Department of Neurology, Glostrup Hospital, University of Copenhagen, Denmark.; Department of Neurology, University of Toulouse, France.; MS Unit, Neurology Department, La Fe University and Polytechnic Hospital, Instituto de investigación Sanitaria La Fe, Spain.; Departments of Neurology and Biomedicine, University Hospital Basel, University of Basel, Switzerland.; MS Centre, SCDU Neurology, Head and Neck Department, AOU Maggiore della Carità, Italy.; Department of Physiology, Anatomy and Genetics and Medical Research Council Functional Genomics Unit, University of Oxford, UK.; Blizard Institute, Queen Mary University of London, Barts and The London School of Medicine and Dentistry, UK [email protected].