Selenium supplementation in radiotherapy patients: do we need to measure selenium levels in serum or blood regularly prior radiotherapy?

Ralph Muecke, Oliver Micke, Lutz Schomburg, Klaus Kisters, Jens Buentzel, Jutta Huebner, Jan Kriz

Journal: Radiation oncology (London, England) 2015;9():289

PMID: 25511764

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Abstract

Considering the review by Puspitasari and colleagues, an additional discussion of the endpoints of the Se supplementation studies described would be helpful. In our view, selenium can safely be given to selenium-deficient cancer patients prior to and during radiotherapy. Therefore, in order to help the radiation oncologist in decision making, we strongly advocate to determine the selenium status prior to and during a potential adjuvant selenium supplementation, e.g. when trying to ease the side-effects of radiation treatment or in the aftercare situation when the selenium status may become insufficient.

Address: Department of Radiotherapy, Lippe Hospital Lemgo, Rintelner Str. 85, D-32657, Lemgo, Germany. [email protected].; Department of Radiotherapy and Radiation Oncology, Ruhr University Bochum, Bochum, Germany. [email protected].; Department of Radiotherapy and Radiation Oncology, Franziskus Hospital, Bielefeld, Germany. [email protected].; Institute for Experimental Endocrinology, Charité Berlin, Germany. [email protected].; Department of Internal Medicine, St. Anna Hospital, Herne, Germany. [email protected].; Department of Otolaryngology, Südharz Hospital, Nordhausen, Germany. [email protected].; Working Group Integrative Oncology, German Cancer Society, Berlin, Germany. [email protected].; Department of Radiotherapy and Radiation Oncology, Münster University Hospital, Münster, Germany. [email protected].

DOI: 10.1186/s13014-014-0289-0

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MeSH Terms: Dietary Supplements, Humans, Neoplasms, Radiation Injuries, Radiotherapy, Selenium