Use of lactoferrin in the newborn: where do we stand?

Deepak Sharma, Anuradha Murki, Srinivas Murki, Oleti Tejo Pratap

Journal: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2016;28(15):1774-8

PMID: 25245229

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Abstract

Sepsis and necrotizing enterocolitis (NEC) cause significant morbidity and mortality in the newborn. Their ill effects persist in spite of appropriate and effective antibiotic therapy. Lactoferrin as an adjunct to antibiotics in the treatment of sepsis or NEC in the newborn may improve the clinical outcomes by enhancing the host defense and modulating the inflammatory response. This review focuses on the various aspects of lactoferrin use in the newborn.

Address: a Department of Neonatology , Fernandez Hospital , Hyderguda , Hyderabad , Andhra Pradesh , India and.

DOI: 10.3109/14767058.2014.968548

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MeSH Terms: Anti-Bacterial Agents, Antifungal Agents, Antiviral Agents, Child Development, Enterocolitis, Necrotizing, Fetal Organ Maturity, Humans, Immunologic Factors, Infant, Newborn, Infant, Premature, Diseases, Lactoferrin, Sepsis