Structure and function of clostridial phospholipases C.

M Jepson, R Titball

Journal: Microbes and infection 2000;2(10):1277-84

PMID: 11008117

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Abstract

A range of clostridial species produce phospholipases C. The zinc metallo phospholipases C have related sequences but different properties. All of these enzymes may be arranged, like alpha-toxin as two-domain proteins. Differences in enzymatic, haemolytic and toxic properties may be explained by differences in amino acids at key positions.

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DOI: 10.1016/s1286-4579(00)01281-8

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MeSH Terms: Amino Acid Sequence, Cell Membrane, Clostridium, Molecular Sequence Data, Phospholipids, Protein Structure, Tertiary, Type C Phospholipases