Over-the-counter enzyme supplements: what a clinician needs to know.

Jithinraj Edakkanambeth Varayil, Brent A Bauer, Ryan T Hurt

Journal: Mayo Clinic proceedings 2014;89(9):1307-12

PMID: 25103998

Full Text on Elsevier Science View on PubMed

Abstract

Over-the-counter (OTC) enzyme use is increasing in frequency in the United States. The numerous health benefit claims by manufacturers are leading to a surge in enzyme use for various conditions and symptoms. Clinicians need to help patients navigate this complex realm and make informed decisions about the use of OTC enzymes. This review focuses on key concepts for health care providers to understand the current evidence, risks, and benefits of OTC enzymes.

Address: Division of General Internal Medicine, Mayo Clinic, Rochester, MN.; Division of General Internal Medicine, Mayo Clinic, Rochester, MN; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN; Division of Endocrinology, Diabetes, Metabolism, and Nutrition, Mayo Clinic, Rochester, MN. Electronic address: [email protected].

DOI: 10.1016/j.mayocp.2014.05.015

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MeSH Terms: Adult, Dietary Supplements, Digestion, Enzyme Therapy, Enzymes, Humans, Inflammation, Myalgia, Neoplasms, Nonprescription Drugs, Osteoarthritis, Pancreatic Diseases