A systematic review: effectiveness of rectal emptying preparation in prostate cancer patients.

Helen A McNair, Linda Wedlake, Irene M Lips, Jervoise Andreyev, Marco Van Vulpen, David Dearnaley

Journal: Practical radiation oncology 2015;4(6):437-47

PMID: 25407867

Abstract

While the importance of a consistent rectal volume during radiation therapy planning and treatment for patients receiving radiation therapy to the prostate is recognized, there is no clear guidance as to the most effective method. This review examines the evidence for the efficacy of rectal preparations. Eighteen papers were found where the primary aim was to investigate a rectal emptying intervention and included 5 different strategies. These included evacuation techniques, dietary interventions, laxatives, and enemas and were either investigated alone or in combination. There is no robust evidence to recommend one rectal emptying strategy over another. Further investigation in adequately powered clinical trials is advised.

Address: Radiotherapy Department, Royal Marsden NHS Foundation Trust and Institute of Cancer Research, Sutton, United Kingdom. Electronic address: [email protected].; Department of Nutrition and Dietetics, Royal Marsden NHS Foundation Trust and Institute of Cancer Research, Sutton, United Kingdom.; Department of Radiation Oncology, University Medical Centre Utrecht, Utrecht, The Netherlands.; Gastroenterology Unit, Royal Marsden NHS Foundation Trust and Institute of Cancer Research, Sutton, United Kingdom.; Academic Urology Unit, Royal Marsden NHS Foundation Trust and Institute of Cancer Research, Sutton, United Kingdom.
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