Fluorescent hydrogels for studying Ca(2+)-dependent reaction-diffusion processes.

Sergey N Semenov, Sjoerd G J Postma, Ilia N Vialshin, Wilhelm T S Huck

Journal: Chemical communications (Cambridge, England) 2014;50(23):3089-92

PMID: 24513909

Full Text on Royal Society of Chemistry View on PubMed

Abstract

Here, we report a convenient experimental platform to study the diffusion of Ca(2+) in the presence of a Ca(2+)-binding protein (Calbindin D28k). This work opens up new possibilities to elucidate the physical chemistry of complex Ca(2+)-dependent reaction-diffusion networks that are abundant in living cells.

Address: Institute for Molecules and Materials, Radboud University Nijmegen, Toernooiveld 1, 6525 ED, Nijmegen, The Netherlands. [email protected].

DOI: 10.1039/c3cc49639b

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https://doi.org/10.1039/c3cc49639b

MeSH Terms: Calbindin 1, Calcium, Cations, Divalent, Diffusion, Fluorescent Dyes, Hydrogels