Biotechnological production and applications of Cordyceps militaris, a valued traditional Chinese medicine.

Jian Dong Cui

Journal: Critical reviews in biotechnology 2016;35(4):475-84

PMID: 24666119

Abstract

Cordyceps militaris is a potential harborer of biometabolites for herbal drugs. For a long time, C. militaris has gained considerable significance in several clinical and biotechnological applications. Much knowledge has been gathered with regard to the C. militaris's importance in the genetic resources, nutritional and environmental requirements, mating behavior and biochemical pharmacological properties. The complete genome of C. militaris has recently been sequenced. This fungus has been the subject of many reviews, but few have focused on its biotechnological production of bioactive constituents. This mini-review focuses on the recent advances in the biotechnological production of bioactive compositions of C. militaris and the latest advances on novel applications from this laboratory and many others.

Address: a Research Center for Fermentation Engineering of Hebei, College of Bioscience and Bioengineering, Hebei University of Science and Technology , Shijiazhang , P R China .; b National Key Laboratory of Biochemical Engineering , Institute of Process Engineering, Chinese Academy of Sciences , HaiDian District , Beijing , P R China , and.; c Key Laboratory of Industry Microbiology , Ministry of Education, Tianjin University of Science and Technology , Tianjin , P R China.

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