Association between the ICAM-1 K469E polymorphism and diabetic retinopathy in Type 2 diabetes mellitus: a meta-analysis.

Hongyan Sun, Xianling Cong, Ran Sun, Chuanwen Wang, Xue Wang, Ya Liu

Journal: Diabetes research and clinical practice 2014;104(2):e46-9

PMID: 24612665

Full Text on Elsevier Science View on PubMed

Abstract

A meta-analysis was conducted to evaluate the association of ICAM-1 K469E gene polymorphism with diabetic retinopathy susceptibility in Type 2 diabetes mellitus. Seven studies involving 1094 cases and 909 controls were included. Current studies suggest that K469E polymorphism in ICAM-1 gene might not affect individual susceptibility to DR.

Address: Tissue Bank, China-Japan Union Hospital of Jilin University, Changchun 130033, Jilin Province, China; Nutrition and Food Hygiene department, School of Public Health, Jilin University, Changchun 130021, Jilin Province, China.; Tissue Bank, China-Japan Union Hospital of Jilin University, Changchun 130033, Jilin Province, China.; Radiological Health Department, Occupation Disease Prevention and Control Center of Jilin Province, Changchun 130061, Jilin Province, China.; Medical Examination Center, China-Japan Union Hospital of Jilin University, Changchun 130033, Jilin Province, China.; Nutrition and Food Hygiene department, School of Public Health, Jilin University, Changchun 130021, Jilin Province, China. Electronic address: [email protected].

DOI: 10.1016/j.diabres.2014.01.028