The heterogeneity of ovarian cancer.

S Hauptmann, I Meinhold-Heerlein

Journal: Archives of gynecology and obstetrics 2014;289(2):237-9

PMID: 24318356

Abstract

Ovarian cancer carries the worst prognosis of all gynecological malignancies. This is mainly due to its resistance against commonly used cytostatic drugs as well as the lack of a screening method for its detection at an early stage. Both basic and translational research have shown over the past decades that ovarian cancer as a medical term includes several types of tumors with different phenotypes, molecular biology, etiology, tumor progression, and even different prognosis. In this issue of Archives of Gynecology and Obstetrics, J. Dietel presents a review article about novel findings of the etiopathogenesis of ovarian cancer and the role that fallopian tubes may play. He also outlines the implied clinical consequences. Here, we give a brief overview of the heterogeneity of ovarian cancer to introduce the topic.

Address: Department of Gynecology and Obstetrics, University Hospital Aachen, Pauwelsstraße 30, 52074, Aachen, Germany, [email protected].

DOI: 10.1007/s00404-013-3114-3

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https://medlineplus.gov/ovariancancer.html

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https://dx.doi.org/10.1007/s00404-013-3114-3

MeSH Terms: Cell Transformation, Neoplastic, Disease Progression, Fallopian Tube Neoplasms, Female, Humans, Molecular Biology, Neoplasm Grading, Neoplasm Invasiveness, Neoplasm Staging, Ovarian Neoplasms, Phenotype, Prognosis, Risk Factors, Survival Analysis