Recurrent aphthous stomatitis.

Sunday O Akintoye, Martin S Greenberg

Journal: Dental clinics of North America 2014;58(2):281-97

PMID: 24655523

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Abstract

Recurrent aphthous stomatitis (RAS) is the most common ulcerative disease affecting the oral mucosa. RAS occurs mostly in healthy individuals and has an atypical clinical presentation in immunocompromised individuals. The etiology of RAS is still unknown, but several local, systemic, immunologic, genetic, allergic, nutritional, and microbial factors, as well as immunosuppressive drugs, have been proposed as causative agents. Clinical management of RAS using topical and systemic therapies is based on severity of symptoms and the frequency, size, and number of lesions. The goals of therapy are to decrease pain and ulcer size, promote healing, and decrease the frequency of recurrence.

Address: Department of Oral Medicine, School of Dental Medicine, University of Pennsylvania, 240 South 40th Street, Philadelphia, PA 19104, USA. Electronic address: [email protected].; Department of Oral Medicine, School of Dental Medicine, University of Pennsylvania, 240 South 40th Street, Philadelphia, PA 19104, USA.

DOI: 10.1016/j.cden.2013.12.002

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MeSH Terms: Humans, Recurrence, Risk Factors, Stomatitis, Aphthous, Wound Healing