Neurologic disorders of mineral metabolism and parathyroid disease.

Lily Agrawal, Zeina Habib, Nicholas V Emanuele

Journal: Handbook of clinical neurology 2014;120():737-48

PMID: 24365349

Full Text on Elsevier Science View on PubMed

Abstract

Disorders of mineral metabolism may cause neurologic manifestations of the central and peripheral nervous systems. This is because plasma calcium stabilizes excitable membranes in the nerve and muscle tissue, magnesium is predominantly intracellular and is required for activation of many intracellular enzymes, and extracellular magnesium affects synaptic transmission. This chapter reviews abnormalities in electrolytes and minerals which can be associated with several neuromuscular symptoms including neuromuscular irritability, mental status changes, cardiac and smooth muscle changes, etc.

Address: Division of Endocrinology and Metabolism, Loyola University Medical Center, Maywood, IL, USA. Electronic address: [email protected].; Division of Endocrinology and Metabolism, Loyola University Medical Center, Maywood, IL, USA.; Division of Endocrinology and Metabolism, Loyola University Medical Center, Maywood, IL, USA; Endocrinology Section, Edward Hines Jr. VA Hospital, Hines, IL, USA.

DOI: 10.1016/B978-0-7020-4087-0.00049-8

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MeSH Terms: Humans, Metabolic Diseases, Minerals, Nervous System Diseases, Parathyroid Diseases