Vaginal misoprostol alone for medical abortion up to 9 weeks of gestation: efficacy and acceptability.

Y M Chan, S W Ngai, O S Tang, P C Ho

Journal: Human reproduction (Oxford, England) 2000;15(5):1159-62

PMID: 10783370

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Abstract

Misoprostol and mifepristone have been shown to be effective for medical abortion up to 9 weeks of gestation. When used alone, the successful complete abortion rate dropped to approximately 60%. It has been demonstrated that by adding water to misoprostol, the success rate rose to 92%. This is the first randomized study to investigate the efficacy of misoprostol and water versus misoprostol alone for first trimester medical abortion in women at

Address: Department of Obstetrics and Gynaecology, University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong SAR, China.

DOI: 10.1093/humrep/15.5.1159

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MeSH Terms: Abortifacient Agents, Nonsteroidal, Abortion, Induced, Administration, Intravaginal, Adolescent, Adult, Female, Gestational Age, Humans, Misoprostol, Nausea, Pregnancy, Pregnancy Trimester, First, Prospective Studies, Tablets, Treatment Outcome, Vomiting, Water