Intracranial atherosclerosis.

Adnan I Qureshi, Louis R Caplan

Journal: Lancet (London, England) 2014;383(9921):984-98

PMID: 24007975

Full Text on Elsevier Science View on PubMed

Abstract

Atherosclerotic disease often involves the intracranial arteries including those encased by cranial bones and dura, and those located in the subarachnoid space. Age, hypertension, and diabetes mellitus are independent risk factors for intracranial atherosclerosis. Intracranial atherosclerosis can result in thromboembolism with or without hypoperfusion leading to transient or permanent cerebral ischaemic events. High rates of recurrent ischaemic stroke and other cardiovascular events mandate early diagnosis and treatment. Present treatment is based on a combination of antiplatelet drugs, optimisation of blood pressure and LDL cholesterol values, and intracranial angioplasty or stent placement, or both, in selected patients.

Address: Zeenat Qureshi Stroke Institute and CentraCare Health, St Cloud, MN, USA. Electronic address: [email protected].; Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA, USA.

DOI: 10.1016/S0140-6736(13)61088-0

Link outs

Free resources

Other Literature Sources:

https://scite.ai/reports/24007975

Subscription / membership required

Full Text Sources:

MeSH Terms: Algorithms, Angioplasty, Brain Ischemia, Cerebrovascular Circulation, Fibrinolytic Agents, Humans, Intracranial Arteriosclerosis, Mental Disorders, Risk Factors, Stents, Stroke