Early management of acute pancreatitis.

Marc G H Besselink, Hjalmar C van Santvoort, Nicolien J Schepers, Olaf J Bakker, Marco J Bruno

Journal: Best practice & research. Clinical gastroenterology 2014;27(5):727-43

PMID: 24160930

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Abstract

Acute pancreatitis is the most common gastro-intestinal indication for acute hospitalization and its incidence continues to rise. In severe pancreatitis, morbidity and mortality remains high and is mainly driven by organ failure and infectious complications. Early management strategies should aim to prevent or treat organ failure and to reduce infectious complications. This review addresses the management of acute pancreatitis in the first hours to days after onset of symptoms, including fluid therapy, nutrition and endoscopic retrograde cholangiography. This review also discusses the recently revised Atlanta classification which provides new uniform terminology, thereby facilitating communication regarding severity and complications of pancreatitis.

Address: Department of Operation Rooms, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands; Department of Gastroenterology and Hepatology, Erasmus Medical Center, Rotterdam, The Netherlands. Electronic address: [email protected].

DOI: 10.1016/j.bpg.2013.08.007

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MeSH Terms: Acute Disease, Cholangiography, Cholangiopancreatography, Endoscopic Retrograde, Fluid Therapy, Humans, Pancreatitis