Atypical femoral fractures: a review of the literature.

Pingal A Desai, Parth A Vyas, Joseph M Lane

Journal: Current osteoporosis reports 2014;11(3):179-87

PMID: 24048722

Abstract

Bisphosphonates are the most commonly used drugs worldwide for treating osteoporosis. Atypical femoral fractures most commonly are associated with prolonged bisphosphonate use. They also may occur with denosumab use or in patients without a history of using these drugs. In this article, we provide a comprehensive review of the mechanism of action of bisphosphonate and the definition, incidence, epidemiology, pathogenesis, diagnosis, management, and prevention of atypical femoral fractures.

Address: Metabolic Bone Disease, Hospital for Special Surgery, 535 East 70th Street, New York, NY, 10021, USA, [email protected].

DOI: 10.1007/s11914-013-0167-y

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https://dx.doi.org/10.1007/s11914-013-0167-y

MeSH Terms: Calcium, Dietary Supplements, Diphosphonates, Disease Management, Femoral Fractures, Femur, Fracture Fixation, Intramedullary, Humans, Incidence, Magnetic Resonance Imaging, Osteoporosis, Radiography, Vitamin D, Withholding Treatment