Athanasios N Saratzis, Steven Goodyear, Hariom Sur, Mahmud Saedon, Christopher Imray, Asif Mahmood
Journal: Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 2014;20(3):315-30
PMID: 23731304
Acute kidney injury (AKI) after any type of intervention negatively impacts mortality, length of hospitalization, and perhaps long-term survival. In the case of endovascular aneurysm repair (EVAR), the incidence of AKI ranges from 1% to 23% for elective and emergency procedures and is lower compared to open repair. The pathophysiology of AKI in EVAR is complex: contrast-induced nephropathy, renal microembolization, and acute tubular necrosis are all implicated. Prevention strategies include hydration, ischemic preconditioning, regional anesthesia, and pharmacological agents. There is no level I evidence regarding the prevention of AKI in EVAR, so this review sought to examine the mechanisms and prevention strategies for this potentially fatal complication.
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