Fulminant viral hepatitis.

Saumya Jayakumar, Raiyan Chowdhury, Carrie Ye, Constantine J Karvellas

Journal: Critical care clinics 2013;29(3):677-97

PMID: 23830658

Full Text on Elsevier Science View on PubMed

Abstract

Acute liver failure (ALF) is a condition wherein the previously healthy liver rapidly deteriorates, resulting in jaundice, encephalopathy, and coagulopathy. There are approximately 2000 cases per year of ALF in the United States. Viral causes (fulminant viral hepatitis [FVH]) are the predominant cause of ALF in developing countries. Given the ease of spread of viral hepatitis and the high morbidity and mortality associated with ALF, a systematic approach to the diagnosis and treatment of FVH is required. In this review, the authors describe the viral causes of ALF and review the intensive care unit management of patients with FVH.

Address: Faculty of Medicine and Dentistry, Division of Gastroenterology, University of Calgary, TRW Building, 3280 Hospital Drive NW, Calgary, Alberta T2N 4Z6, Canada.

DOI: 10.1016/j.ccc.2013.03.013

Link outs

Free resources

Other Literature Sources:

https://scite.ai/reports/23830658

Subscription / membership required

Full Text Sources:

MeSH Terms: Acetylcysteine, Adult, Brain Edema, Developing Countries, Female, Hepatectomy, Hepatitis, Viral, Human, Herpesviridae, Humans, Hypothermia, Induced, Immunocompromised Host, Intensive Care Units, Intubation, Intratracheal, Liver Failure, Acute, Liver Transplantation, Pregnancy, Pregnancy Complications, Infectious, Prognosis, Viral Hepatitis Vaccines