Susceptibility weighted imaging in the evaluation of movement disorders.

D R Hingwala, C Kesavadas, B Thomas, T R Kapilamoorthy

Journal: Clinical radiology 2013;68(6):e338-48

PMID: 23541097

Full Text on Elsevier Science View on PubMed

Abstract

Movement disorders are neurodegenerative disorders associated with abnormalities of brain iron deposition. In this presentation, we aim to describe the role of susceptibility weighted imaging (SWI) in the imaging of patients with movement disorders and differentiate between the various disorders. SWI is a high-resolution, fully velocity-encoded gradient-echo magnetic resonance imaging (MRI) sequence that consists of using both magnitude and phase information. We describe briefly the physics behind this sequence and the post-processing techniques used. The anatomy of the midbrain and basal ganglia in normal subjects on SWI is covered. A number of neurodegenerative disorders are associated with abnormal iron deposition, which can be detected due to the susceptibility effects.

Address: Department of Imaging Sciences and Interventional Radiology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, India.

DOI: 10.1016/j.crad.2012.12.003

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MeSH Terms: Basal Ganglia, Humans, Iron, Magnetic Resonance Imaging, Mesencephalon, Movement Disorders