Biology of renal aging in humans.

B Clark

Journal: Advances in renal replacement therapy 2000;7(1):11-21

PMID: 10672914

Full Text on Elsevier Science View on PubMed

Abstract

Advancing age is usually accompanied by a decline in glomerular filtration rate and an increased incidence of certain renal and electrolyte disorders. These include an increased susceptibility to acute renal failure, hypo- and hypernatremia, hyperkalemia, and hypertension. This report discusses anatomic and physiological observations related to the aged human kidney and explores the various theories and postulated mechanisms underlying these changes.

Address: Allegheny General Hospital, Pittsburgh, PA 15212, USA.

DOI: 10.1016/s1073-4449(00)70002-1

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https://linkinghub.elsevier.com/retrieve/pii/S1073...

MeSH Terms: Aging, Body Water, Fibrosis, Glomerulosclerosis, Focal Segmental, Homeostasis, Humans, Kidney, Potassium, Sodium