Metastasis to the choroid plexus from thyroid cancer: case report.

Yosuke Kitagawa, Fumi Higuchi, Yoshihiro Abe, Hadzuki Matsuda, Phyo Kim, Keisuke Ueki

Journal: Neurologia medico-chirurgica 2015;53(11):832-6

PMID: 24162238

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Abstract

Thyroid cancer is not a common primary cancer causing intracranial metastasis. Here we report a 74-year-old woman with magnetic resonance imaging (MRI) demonstrating a 4 cm round, heterogeneously enhancing mass in the trigone of the right lateral ventricle. Systemic screening by computed tomography (CT) examination detected a 20 mm nodule with calcification in the thyroid, multiple well circumscribed nodules in bilateral lung filed, and a bone metastasis to the right dorsal rib. Cerebral angiography demonstrated a hypervascular mass fed from anterior and posterior choroidal arteries. Tumor biopsy via parietal transcortical approach confirmed a thyroid carcinoma metastasis to the choroid plexus. Of the 33 reported cases of choroid plexus metastasis, 14 (42%) are from kidney and 3 (9%) from thyroid cancer, which appears to be overrepresented considering their prevalence among all brain metastasis. There may be seed-and-soil relationship between thyroid cancer and choroid plexus.

Address: Department of Neurosurgery, Dokkyo Medical University.

DOI: 10.2176/nmc.cr2012-0238