The plant non-specific phospholipase C gene family. Novel competitors in lipid signalling.

Igor Pokotylo, Přemysl Pejchar, Martin Potocký, Daniela Kocourková, Zuzana Krčková, Eric Ruelland, Volodymyr Kravets, Jan Martinec

Journal: Progress in lipid research 2013;52(1):62-79

PMID: 23089468

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Abstract

Non-specific phospholipases C (NPCs) were discovered as a novel type of plant phospholipid-cleaving enzyme homologous to bacterial phosphatidylcholine-specific phospholipases C and responsible for lipid conversion during phosphate-limiting conditions. The six-gene family was established in Arabidopsis, and growing evidence suggests the involvement of two articles NPCs in biotic and abiotic stress responses as well as phytohormone actions. In addition, the diacylglycerol produced via NPCs is postulated to participate in membrane remodelling, general lipid metabolism and cross-talk with other phospholipid signalling systems in plants. This review summarises information concerning this new plant protein family and focusses on its sequence analysis, biochemical properties, cellular and tissue distribution and physiological functions. Possible modes of action are also discussed.

Address: Institute of Bioorganic Chemistry and Petrochemistry, National Academy of Sciences of Ukraine, Kyiv, Ukraine.

DOI: 10.1016/j.plipres.2012.09.001