Tumoral calcinosis: a dental literature review and case report.

Ana Krstevska, Sarah Gale, Fiona Blair

Journal: Dental update 2012;39(6):416-8, 421

PMID: 22928454

Abstract

UNLABELLED

Tumoral calcinosis (TC) is a rare familial disease characterized by abnormal peri-articular calcification in affected joints, without any associated renal, metabolic or collagen vascular disease. It is characterized by usual hyperphosphataemia with normal serum calcium and alkaline phosphatase values. There are only a few reported cases ofTC patients with dental findings. This article reviews the dental literature and describes progressive gingival, alveolar and mandibular tori enlargement in a 41-year-old female from Zimbabwe with tumoral calcinosis.

CLINICAL RELEVANCE

Tumoral calcinosis is a rare disorder of mineral metabolism with oral manifestations.

Address: Birmingham Dental Hospital, Birmingham B4 6NN, UK.

DOI: 10.12968/denu.2012.39.6.416

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MeSH Terms: Adult, Calcinosis, Crown Lengthening, Fatal Outcome, Female, Genes, Recessive, Gingival Overgrowth, Humans, Hyperostosis, Jaw Diseases, Joint Diseases, Mutation, N-Acetylgalactosaminyltransferases, Zimbabwe, Polypeptide N-acetylgalactosaminyltransferase