Psychotropic medications and other non-hormonal treatments for premenstrual disorders.

Teri Pearlstein

Journal: Menopause international 2012;18(2):60-4

PMID: 22611223

Abstract

Selective serotonin re-uptake inhibitors have well-established efficacy for severe premenstrual syndrome and premenstrual dysphoric disorder. Efficacy has been reported with both continuous dosing (all cycle) and intermittent or luteal phase dosing (from ovulation to menses). Efficacy may be less with intermittent dosing, particularly for premenstrual physical symptoms. The efficacy of symptom-onset dosing (medication taken only on luteal days when symptoms occur) needs further systematic study. Women going through the menopausal transition may need to adjust their antidepressant dosing regimen due to the change in frequency of menstruation. Anxiolytics, calcium, chasteberry and cognitive-behaviour therapy may also have a role in the treatment of premenstrual symptoms.

Address: Alpert Medical School of Brown University, Providence, RI 02912, USA. [email protected]

DOI: 10.1258/mi.2012.012010

Link outs

Free resources

Medical:

https://medlineplus.gov/premenstrualsyndrome.html

MeSH Terms: Alprazolam, Anti-Anxiety Agents, Antidepressive Agents, Calcium Compounds, Cognitive Behavioral Therapy, Diet, Exercise, Female, Humans, Life Style, Norepinephrine, Perimenopause, Phytotherapy, Premenstrual Syndrome, Randomized Controlled Trials as Topic, Selective Serotonin Reuptake Inhibitors