Clinical nutrition, body composition and oncology: a critical literature review of the synergies.

Claude Pichard, Nathalie Jacquelin-Ravel

Journal: Critical reviews in oncology/hematology 2013;84(1):37-46

PMID: 22522184

Full Text on Elsevier Science View on PubMed

Abstract

PURPOSE OF THE RESEARCH

Review the oncology and clinical nutrition literature to highlight the synergies between those two subjects. This review focuses on diagnostic of lean body wasting and the recent improvements in measuring body composition to monitor the response to nutrition during optimal oncology treatment.

PRINCIPAL RESULTS

Nutrition support in cancer patients has made major progresses. A variety of advanced tools allow monitoring and explaining weight loss, body composition changes and metabolic alterations. Body composition is more accurate than body surface area to determine chemotherapeutic drug dosing. As with any therapeutic approach, clinical nutrition has a better risk-benefit ratio if implemented when indicated rather than used routinely. Body composition measurements are helpful for a better understanding of the host-tumor interactions during cancer treatment and nutrition support.

MAJOR CONCLUSIONS

Nutrition support based on body composition analysis may significantly contribute to optimize current oncology treatment and clinical outcomes.

Address: Clinical Nutrition, Clinique de Genolier, Genolier, Switzerland. [email protected]

DOI: 10.1016/j.critrevonc.2012.02.001