Life-threatening bleeding under vitamin K antagonists in spite of an INR in the therapeutic range.

Mathilde Gavillet, Claire Abbal, Sabine Schmidt, Jasmine Nötzli, Jean-François Lambert, Anne Angelillo-Scherrer

Journal: Journal of thrombosis and thrombolysis 2011;32(2):232-7

PMID: 21416391

Full Text on Ovid Technologies, Inc. View on PubMed

Abstract

Address: Service and Central Laboratory of Hematology, Centre Hospitalier Universitaire Vaudois and University of Lausanne, rue du Bugnon 46, CH-1011 Lausanne, Switzerland.

DOI: 10.1007/s11239-011-0580-y

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https://doi.org/10.1007/s11239-011-0580-y

MeSH Terms: Acenocoumarol, Amino Acid Substitution, Anticoagulants, Factor IX, Hematoma, Hemothorax, Humans, International Normalized Ratio, Laryngeal Diseases, Male, Middle Aged, Mutation, Missense, Pedigree, Radiography, Vitamin K