Pneumocystis jiroveci pneumonia in an infant with severe folate deficiency.

Gemma Crighton, Gabrielle Haeusler, Nalini Pati, Tom G Connell

Journal: The Pediatric infectious disease journal 2011;30(8):721-3

PMID: 21346686

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Abstract

Pneumocystis jiroveci pneumonia is rare in immunocompetent children. Severe folate deficiency affects T cell function, potentially increasing susceptibility to opportunistic pathogens. We report the case of an 11-month-old child who developed P. jiroveci pneumonia in the setting of severe nutritional folate deficiency and review the literature regarding the influence of folate on immunity.

Address: Department of Haematology, Royal Children's Hospital Melbourne, Parkville, Victoria, Australia.

DOI: 10.1097/INF.0b013e31820fc6e3

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MeSH Terms: Folic Acid Deficiency, Humans, Infant, Male, Pneumocystis carinii, Pneumonia, Pneumocystis