The removal of protein-bound solutes by dialysis.

Timothy W Meyer

Journal: Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 2012;22(1):203-6

PMID: 22200443

Full Text on Elsevier Science View on PubMed

Abstract

Protein-bound solutes that accumulate in plasma when the kidneys fail are poorly cleared by conventional dialysis. Means have been developed to reduce the levels of such solutes, either by modifying the dialysis procedure to increase their clearance or by limiting their production. A trial testing whether reducing bound solute levels clinically benefits dialysis patients is required to determine whether these measures should be adopted in routine clinical practice.

Published by Elsevier Inc.

Address: Department of Medicine/Nephrology, VA Palo Alto HCS, Palo Alto, California 94303, USA. [email protected]

DOI: 10.1053/j.jrn.2011.10.011

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MeSH Terms: Adsorption, Blood Proteins, Cresols, Humans, Indican, Kidney, Proteins, Renal Dialysis, Sulfuric Acid Esters, Urea, Uremia