Strategies to adapt cellular processes to nutrient availability in bacteria.

Bacteria are able to adapt to nutrient availability in the environment. For example, when nutritional conditions are not favorable, bacterial size can be reduced and duplication time can be significantly extended in comparison to rich growth conditions. These observations suggest that essential cellular processes like cell division, morphogenesis and chromosome dynamics are highly coordinated with central metabolism to ensure the production of fit progeny. The aim of this review is to provide an overview extending from physiological observations done more than fifty years ago to recent discoveries showing strategies to control essential functions in relation with metabolism in the model bacterium Bacillus subtilis.