Microarray for epigenetic changes: gene expression arrays.

Hilary A A Colyer, Richard N Armstrong, Ken I Mills

Journal: Methods in molecular biology (Clifton, N.J.) 2012;863():319-28

PMID: 22359303

Abstract

Microarrays can be used to examine changes involving all aspects of the epigenetic interactions. As the relationship between DNA methylation, histone modifications, and gene expression is elucidated, an important aspect to investigate is how the epigenetic status regulates the cell through differential expression of genes. This can provide data from work including experimental drug investigations from cell line models, or more directly patient comparison data.

Address: Haematology, Centre for Cancer Research and Cell Biology Belfast, Queen's University Belfast, Belfast, Northern Ireland, UK. [email protected]

DOI: 10.1007/978-1-61779-612-8_20

Link outs

Free resources

Research Materials:

https://antibodies.cancer.gov/detail/CPTC-HLA-B-1

Subscription / membership required

Full Text Sources:

https://doi.org/10.1007/978-1-61779-612-8_20

MeSH Terms: Biotin, DNA, Complementary, Epigenesis, Genetic, Epigenomics, Gene Expression Profiling, Microarray Analysis