Metabolic engineering of microorganisms for vitamin C production.

Jian Chen, Guocheng Du, Jingwen Zhou

Journal: Sub-cellular biochemistry 2014;64():241-59

PMID: 23080254

Abstract

Vitamin C, an important organic acid, is widely used in the industries of pharmaceuticals, cosmetics, food, beverage and feed additives. Compared with the Reichstein method, biotechnological production of vitamin C is an attractive approach due to the low cost and high product quality. In this chapter, biosynthesis of vitamin C, including one-step fermentation processes and two-step fermentation processes are discussed and compared. Furthermore, the prospects of the biotechnological production of vitamin C are also presented.

Address: School of Biotechnology, Jiangnan University, 1800 Lihu Road, Wuxi, 214122, China.

DOI: 10.1007/978-94-007-5055-5_12

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https://dx.doi.org/10.1007/978-94-007-5055-5_12

MeSH Terms: Ascorbic Acid, Bacillus megaterium, Fermentation, Glucose, Humans, Metabolic Engineering, Microbial Interactions, Microbiological Phenomena, Temperature