Yi-Ping Zhan, Xin-En Huang, Jie Cao, Yan-Yan Lu, Xue-Yan Wu, Jin Liu, Xia Xu, Jin Xiang, Li-Hong Ye
Journal: Asian Pacific journal of cancer prevention : APJCP 2013;13(10):5319-21
PMID: 23244156
OBJECTIVE
To observe efficacy and side effects, as well as the impact on quality of life, of Kanglaite® (Coix Seed Oil) injections combined with chemotherapy in the treatment of advanced gastric cancer patiensts.
METHOD
A consecutive cohort of 60 patients were divided into two groups:the experimental group receiving Kanglaite® Injection combined with chemotherapy and the control group with chemotherapy alone. After more than two courses of treatment, efficacy, quality of life and side effects were evaluated.
RESULTS
The response rate and KPS score of experimental group were significantly improved as compared with those of the control group(P<0.05). In addition, gastrointestinal reactions and bone marrow suppression were significantly lower than in the control group(P<0.05).
CONCLUSIONS
Kanglaite® Injection enhanced efficacy and reduced the side effects of chemotherapy, improving quality of life of gastric cancer patients; use of Kanglaite® injections deserves to be further investigated in randomized control clinical trails.
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