Acute toxoplasmosis mimicking melanoma metastases: review of conditions causing false-positive results on (18)F-FDG PET/CT.

K Ivanova, K Glatz, A Zippelius, G Nicolas, P Itin

Journal: Dermatology (Basel, Switzerland) 2013;225(4):349-53

PMID: 23406996

Full Text on S. Karger AG, Basel, Switzerland View on PubMed

Abstract

Invasive malignant melanoma is the most common fatal form of skin cancer. Fluorine-18-fluorodeoxyglucose positron emission tomography-computed tomography demonstrates a very high sensitivity and specificity for the detection of melanoma metastases. Here, we report an unusual case of toxoplasma lymphadenitis in a male adult patient mimicking a malignant cervical lymphadenopathy. Toxoplasmosis is a zoonosis caused by the intracellular parasite Toxoplasma gondii, which is usually asymptomatic in immunocompetent hosts.

Address: Department of Dermatology, University Hospital Basel, Basel, Switzerland. [email protected]

DOI: 10.1159/000346333

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MeSH Terms: Antibodies, Protozoan, Diagnosis, Differential, False Positive Reactions, Fluorodeoxyglucose F18, Humans, Immunoglobulin G, Immunoglobulin M, Lymphadenitis, Male, Melanoma, Middle Aged, Multimodal Imaging, Positron-Emission Tomography, Predictive Value of Tests, Skin Neoplasms, Tomography, X-Ray Computed, Toxoplasmosis