Acquired plate-like osteoma cutis.

Julie Chu, Rishi Patel, Neelam Vashi

Journal: Dermatology online journal 2012;17(10):1

PMID: 22031627

Free Full Text on Arthur C Huntley MD, California Digital Library View on PubMed

Abstract

Plate-like osteoma cutis is a rare disorder that has been historically classified as a congenital syndrome. It has a possible relationship to a mutation in the gene (GNAS1) that encodes the α-subunit of the stimulatory G protein, which regulates adenyl cyclase activity. We report a case of extensive plaque-like masses on the scalp and face with no abnormalities in calcium or phosphate metabolism and no preceding inflammatory cutaneous conditions. With less than ten reported cases, to our knowledge, this is one the few cases of acquired plate-like osteoma cutis described in the literature.

Address: Department of Dermatology, New York University, New York, New York, USA.

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http://dermatology.cdlib.org/1710/2010-10/1_2010-1...

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https://medlineplus.gov/skinconditions.html

MeSH Terms: Calcium, Chromogranins, Facial Dermatoses, GTP-Binding Protein alpha Subunits, Gs, Humans, Male, Middle Aged, Ossification, Heterotopic, Osteoma, Phosphorus, Scalp Dermatoses, Skin Diseases, Thigh, Thorax