Convergent strategies in biosynthesis.

Tohru Dairi, Tomohisa Kuzuyama, Makoto Nishiyama, Isao Fujii

Journal: Natural product reports 2011;28(6):1054-86

PMID: 21547300

Full Text on Royal Society of Chemistry View on PubMed

Abstract

This review article focuses on how nature sometimes solves the same problem in the biosynthesis of small molecules but using very different approaches. Four examples, involving isopentenyl diphosphate, menaquinone, lysine, and aromatic polyketides, are highlighted that represent different strategies in convergent metabolism.

Address: Faculty of Engineering and Graduate School of Engineering, Hokkaido University, Sapporo 060-8628, Japan. [email protected]

DOI: 10.1039/c0np00047g

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https://doi.org/10.1039/c0np00047g

MeSH Terms: Bacteria, Biological Products, Lysine, Macrolides, Molecular Structure, Terpenes, Vitamin K 2