Effects of I-131 therapy on gonads and pregnancy outcome in patients with thyroid cancer.

Andreas Fotopoulos, Chrissa Sioka

Journal: Fertility and sterility 2011;95(5):1552-9

PMID: 21300333

Free Full Text on Elsevier Science View on PubMed

Abstract

We examined the effects of I-131 therapy for thyroid cancer on female and male gonads and pregnancy outcome. After an extensive review of the published literature we concluded that ablative administration of I-131 therapy may result in transient abnormalities of ovarian and testicular function, but subsequent pregnancies are safe without any significant consequences to offspring outcome.

Address: Department of Nuclear Medicine, University Hospital of Ioannina, Ioannina, Greece. [email protected]

DOI: 10.1016/j.fertnstert.2011.01.017

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MeSH Terms: Carcinoma, Papillary, Follicular, Female, Gonads, Humans, Iodine Radioisotopes, Lactation, Male, Pregnancy, Pregnancy Complications, Neoplastic, Pregnancy Outcome, Thyroid Neoplasms