A randomized crossover study to determine relative bioequivalence of tenofovir, emtricitabine, and efavirenz (Atripla) fixed-dose combination tablet compared with a compounded oral liquid formulation derived from the tablet.

Jennifer King, Matthew McCall, Anthony Cannella, Michael Anne Markiewicz, Amanda James, Chantelle B Hood, Edward P Acosta

Journal: Journal of acquired immune deficiency syndromes (1999) 2011;56(5):e130-2

PMID: 22046602

Full Text on Ovid Technologies, Inc. View on PubMed

Abstract

DOI: 10.1097/qai.0b013e31820eefbe

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MeSH Terms: Adenine, Administration, Oral, Adult, Aged, Cross-Over Studies, Deoxycytidine, Drug Combinations, Drug Compounding, Efavirenz, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination, Female, Humans, Male, Middle Aged, Organophosphonates, Oxazines, Reverse Transcriptase Inhibitors, Tablets, Therapeutic Equivalency, Treatment Outcome, Water

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