Foldamers containing γ-amino acid residues or their analogues: structural features and applications.

Over the past 20 years, the field of foldamers has rapidly increased. Many β-peptides have already been described and shown interesting properties. γ-Peptides have more recently emerged but seem to be very interesting as well. In this review, we will cover every peptidomimetic oligomer that contains a γ-amino acid or an analogue and presents a structural feature. It includes γ-peptides but also hybrid α-γ peptides, β-γ peptides and analogues such as oligoureas or aminoxy acids. We will present the biological properties of these oligomers.