Gastric dysmotility after liquid bolus ingestion in systemic sclerosis: an ultrasonographic study.

Franco Cozzi, Giancarlo Parisi, Luca Ciprian, Arianna Bullo, Silvia Cardarelli, Michela Rizzo, Paolo Sfriso, Leonardo Punzi

Journal: Rheumatology international 2012;32(5):1219-23

PMID: 21258796

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Abstract

Gastric involvement appears quite commonly in systemic sclerosis (SSc). The aim of this study was to evaluate gastric wall motility using ultrasonography, a noninvasive method able to track both filling and emptying of fundus and antrum. The study was performed in 20 SSc patients and 20 healthy control subjects. Gastric filling and emptying were evaluated by transabdominal ultrasonography, measuring changes in fundus and antral areas over a 1-h period after ingestion of a liquid bolus (500 ml of mineral water). Areas of both gastric fundus and antrum at basal evaluation were found to be smaller in SSc patients than in healthy controls. Gastric filling was significantly reduced after ingestion of liquid bolus. Gastric emptying was delayed both in fundus and antrum. No significant differences of gastric wall motility have been observed in different subsets of SSc patients. Our findings show that gastric dysmotility is frequent and severe in SSc patients, contributing to the gastrointestinal disturbances which are very common in this disease.

Address: Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy. [email protected]

DOI: 10.1007/s00296-010-1779-5

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https://dx.doi.org/10.1007/s00296-010-1779-5

MeSH Terms: Adult, Aged, Case-Control Studies, Drinking, Female, Gastric Emptying, Gastric Fundus, Gastrointestinal Motility, Gastroparesis, Humans, Italy, Male, Middle Aged, Mineral Waters, Predictive Value of Tests, Pyloric Antrum, Scleroderma, Systemic, Time Factors, Ultrasonography