Choice of modality with the use of high-performance membrane and evaluation for clinical effects.

Ikuto Masakane

Journal: Contributions to nephrology 2012;173():84-94

PMID: 21865780

Full Text on S. Karger AG, Basel, Switzerland View on PubMed

Abstract

The golden target for dialysis therapy should be to guarantee longer survival and to give a higher quality of life without dialysis-related complications. In order to achieve this target, the choice of dialysis modality and membrane is essential but we have not yet established what the best choice for a dialysis modality and membrane are. Generally, we choose a dialysis modality for better solute removal and better biocompatibility. In this issue we would like to propose that the patients' preference for dialysis therapy is a useful parameter in prescribing the dialysis modality. In our recent experience, chronic dialysis patients have had preferences on a dialysis modality and membrane, those being PMMA, EVAL, AN-69 and pre-dilution online HDF. These modalities could relieve them of uncomfortable dialysis-related symptoms such as insomnia, itchiness, irritability, and so on. Other characteristics of these modalities are of a nutritional advantage, a broad removal pattern of uremic toxins including low-molecular-weight protein and protein-bound uremic toxins, and good biocompatibility free from chemical components of dialysis membrane. In conclusion, patients' symptoms could be a useful parameter to choose a dialysis modality and membrane.

Address: Yabuki Shima Clinic, Yamagata, Japan.

DOI: 10.1159/000328959

Link outs

Free resources

Medical:

https://medlineplus.gov/dialysis.html

Subscription / membership required

Full Text Sources:

https://doi.org/10.1159/000328959

MeSH Terms: Acrylic Resins, Acrylonitrile, Amyloidosis, Arthralgia, Benzhydryl Compounds, Biocompatible Materials, Hemodiafiltration, Humans, Male, Malnutrition, Membranes, Artificial, Middle Aged, Molecular Weight, Phenols, Polymethyl Methacrylate, Polyvinyls, Povidone, Pruritus, Randomized Controlled Trials as Topic, Renal Dialysis, Serum Albumin, Surveys and Questionnaires, Survival Analysis, Uremia, beta 2-Microglobulin