Erythrocytes carotenoids after astaxanthin supplementation in middle-aged and senior Japanese subjects.

Taiki Miyazawa, Kiyotaka Nakagawa, Fumiko Kimura, Akira Satoh, Teruo Miyazawa

Journal: Journal of oleo science 2012;60(10):495-9

PMID: 21937848

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Abstract

A randomized, double-blind human trial was conducted to assess the effect of 4- or 12-week astaxanthin supplementation (1 or 3 mg/day) on the carotenoid compositions of erythrocytes in Japanese middle-aged and senior subjects. Erythrocyte astaxanthin concentrations after 4- or 12-weeks of supplementation (3 mg/day) was significantly higher than after placebo or 1 mg astaxanthin supplementations. No differences were observed in either the carotenoid compositions or the phospholipid hydroperoxide concentrations in erythrocytes after astaxanthin intake in both the 1 and 3 mg/day groups.

Address: Food and Biodynamic Chemistry Laboratory, Graduate School of Agricultural Science, Tohoku University, Japan. [email protected]

DOI: 10.5650/jos.60.495

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MeSH Terms: Adult, Aged, Carotenoids, Double-Blind Method, Erythrocytes, Flow Injection Analysis, Humans, Japan, Middle Aged, Tandem Mass Spectrometry, Xanthophylls